I have been attending the biannual Clinical Informatics for Cancer Centers (CI4CC) conference and there has been a fair amount of dicussion of ClinicalTrials.gov as a resource for enhancing patient engagement, trial recruitment, and results reporting. There are a number of approaches to search and access in bulk ClinicalTrials.gov data. The ones that I address here are: The CTRP RESTful API. The ClinicalTrials.gov API. The Access to Aggregate Content of ClinicalTrials.